the Lord God made garments of skin for Adam and his wife and clothed them.
We should look at the final kindness of God. He replaces their inadequate coverings of leaves and provides animal skins. It is surely significant that these coverings provided by God required death and the shedding of blood. I wonder too was this act of kindness by God something they noticed, and should Cain have remembered it before his act of worship?
But God now drives them out of Eden and stations an angel who camps there to guard the entrance to the tree of life. All is overturned here.
This first act of disobedience has had dire consequences for all of humanity. Consequences we all live with. We still strive to get back to the tree of life. We seek to postpone death, stay young, with trim bodies. Much genetic research is currently directed at halting or delaying the aging process. But the angel stands there. And we fall again and again in our human arrogance and hubris.